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DeCS
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Descriptor English:
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Rioprostil
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Descriptor Spanish:
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Rioprostilo
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Descriptor Portuguese:
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Rioprostila
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Synonyms English:
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ORF 15927
ORF-15927
ORF15927
RWJ 15927
RWJ-15927
RWJ15927
TR 4698
TR-4698
TR4698
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Tree Number:
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D10.251.355.255.550.775.450.750
D23.469.050.175.725.775.450.750
D23.469.700.660.750
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Definition English:
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A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies. |
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Pharmacological Action:
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Anti-Ulcer Agents
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History Note English:
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92; was RIOPROSTIL (NM) 1985-91
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Allowable Qualifiers English:
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Record Number:
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29838
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Unique Identifier:
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D016630
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Occurrence in VHL:
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Similar:
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DeCS
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